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2019;10 doi: 10.3389/fimmu.2019.02759

Therapeutic monoclonal antibodies, including PD1/PDL1 inhibitors, are eliminated via nonspecific catabolic pathways and do not directly interact with cytochrome P450 enzymes or drug transporters

The top choice is "Haematococcus pluvialis," a microalgae that produces the highest-quality, natural astaxanthin

Its metabolism is catalysed by a number of enzymes that require B-vitamins as cofactors, with homocysteine levels being particularly responsive to folate status