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These findings indicate that while the stem cell properties of epSPCs remain largely intact, their differentiation potential is altered in the context of ALS, with a skewing toward reactive glial phenotypes and increased neuronal output

TXNDC12 can also be involved in endoplasmic reticulum stress by regulating the activation of ATF6 during the unfolded protein response by becoming a mixed disulfide with activating activated transcription factor 6 (ATF6) [13, 14]

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"food noise" is the near-universal term for the appetite change

The purpose of this review is to comprehensively investigate of the emerging understanding of the pleiotropic role of the carnitine pool, carnitine/acylcarnitines are not only auxiliaries or metabolites of fatty acid oxidation, but also play more complex and diverse roles, including energy metabolism, mitochondrial homeostasis, epigenetic regulation, regulation of inflammation and the immune system, tumor biology, signal transduction, and neuroprotection

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