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GPX4 In mammalian tissues, the major mechanism to detoxify H 2 O 2 -induced ROS is dependent on glutathione peroxidases (GPXs)

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The specific subcellular compartment for lactate uptake and oxidation, whether in the cytoplasm or mitochondria, remains controversial

The pathways that met the statistical threshold ( log[p-value] 1.3) and the proteins assigned to each canonical pathway are listed in Table 4

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