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Long-term disc health requires ongoing attention to the factors that caused or contributed to the herniation in the first place

2008 Jan 24 [cited 2025 Apr 19];358(4):e4

TrkB neurotrophic activities are blocked by alpha-synuclein, triggering dopaminergic cell death in Parkinson's disease

As a result, it induces ferroptosis, a form of non-apoptotic cell death [1]

Furthermore, the primary sources of free radicals during cerebral ischaemia-reperfusion include calcium-dependent oxidative enzymes such as xanthine oxidase, NADPH oxidase, and nitric oxide synthase, as well as the degradation of membrane and mitochondrial phospholipids [14]