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Although IN delivery of DFO appears to be well tolerated in animal models, repeated administration can potentially cause nasal irritation or epistaxis (nosebleed), which can induce inflammation or reduced drug uptake

These changes influence aqueous production and outflow and disrupt the homeostatic mechanisms of intraocular pressure control [100]

Glyteine is the body's natural precursor to glutathione (see figure 3) and the only product on the market that can efficiently raise cellular glutathione by bypassing this defective enzyme

The baseline characters were comparable between two groups

doi: 10.1111/j.1745-7262.2006.00198.x