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Evidence from a systematic review and meta-analysis

and Shantou S.E.Z

219 In addition, 23 serum metabolites, including myoinositol, glycerophosphoinositol, fumarate, cysteine sulfonic acid, and a modified version of fibrinogen peptide B (mFBP), are able to discriminate COPD from controls

Moreover, as cystine is an extracellular source of cysteine, cystine uptake is facilitated by the efflux of glutamate via the xCT antiporter

mRNA analysis demonstrated that the TA-PVP encapsulation increases the expression of the anti-inflammatory gene Arg1 and decreases the expression of proinflammatory chemokines Ccl2, Ccl5, and Cxcl10, confirming the ability of TA-PVP to promote the anti-inflammatory innate immune phenotype and elicit localized immunosuppression

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