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We found similarly affected genes in both lines, with only a small number positively enriched at day 15 (Supplementary Fig

Mechanistically, lactate accumulation, driven by PKM2, enhances Twist1-K150la, which in turn facilitates Twist1 phosphorylation, nuclear translocation, and regulation of TGFB1 transcription, thereby inducing an EndoMT-associated fibrotic phenotype in ischemic flaps

The SDGs (20152030) comprise 17 interconnected objectives intended to guide the international community towards a more equitable and sustainable future, with 169 specific targets for different dimensions of social health, economic, and institutional improvement

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Low levels of Vitamin B12 are rare in most healthy adults because the human liver stores it over time