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[PubMed] [Google Scholar] 29.Vigneron A., Vousden K.H

At a time when many of the standard drugs used to treat such diseases are frequently ineffective, these new targeting directives provide a timely opportunity

This strategy has been applied to dulaglutide, where two GLP-1 molecules are fused to the Fc fragment of IgG4, increasing the half-life while reducing the renal elimination due to the increased molecular weight