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The definition and diagnostic criteria of minimal HE were unclear in two previous clinical trials conducted in patients with minimal HE [15,16]

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7.4 Fluorescent probe-based imaging markers At present, the most common fluorescence probe targets for PD biomarkers include -Syn, type B monoamine oxidase (MAO-B), dopamine-associated proteins (DATs and DARs), metal ions, ROS clusters, etc

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