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10.1016/j.jep.2023.116670 49 KongF.BuseD

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Mechanistically, JUH083 decreased immunosuppressive cells such as monocytes and myeloid-derived suppressor cells, regulatory T cells, pro-tumorigenic CD4 + Th17 cells, and boosted the infiltration of CD8 + T cells and CD4 + Th1 cells

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To verify the proposed mechanism of action of NMN, we studied longterm NMN supplementation and its impact on ovarian health and discovered that NMN helps prevent ovarian atrophy