dsip danaher Corporation Dana E. Sless DO, FAAP

Theoretical considerations include: Potential interactions requiring monitoring: Other fat-loss agents or thermogenics (additive effects), growth hormone or growth hormone secretagogues (mechanism overlap), medications affecting glucose metabolism (monitor blood sugar despite AOD-9604s neutral glycemic effects)

doi: 10.1002/EJI.201545708 24 SakaguchiSSakaguchiNAsanoMItohMTodaM

NAD+ participates in over 400 enzymatic reactions, including the core pathways of energy metabolism, DNA repair, and cellular signaling

While we dont yet have precise human data, BPC-157 appears to be: Rapidly absorbed into circulation Short-acting in plasma , but with longer-lasting biological effects due to downstream healing responses Cleared from the bloodstream in several hours , though effects may persist for days or weeks BPC-157 initiates angiogenic and cytoprotective signaling cascades that extend beyond its direct presence in the bloodstream. Sikiric, P

The study demonstrated that MOTS-c levels in the blood of centenarians, individuals who have survived to 100 years and older, were significantly higher than in age-matched individuals with shorter lifespans, and resembled levels seen in much younger adults [2]

10 JEN.S32843: 101120