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In human studies, singlephoton emission computed tomography (SPECT) shows hypofrontality patients suffering from schizophrenia [22]

This led to the development of a HER2 targeted monoclonal antibody, trastuzumab, which prevents ligand association with HER2 and ablates pathway activity, significantly improving patient survival (Slamon et al., 2001

Written informed consent was obtained from the minor(s) legal guardian/next of kin for the publication of any potentially identifiable images or data included in this article

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doi: 10.1007/s00774-022-01375-x 125 ParamsothySWalshAJBorodyTSamuelDvan den BogaerdeJLeongRWet al

The level of ROS oscillates in time, in the case of the need to ensure physiological functions, the concentration of ROS increases rapidly, and conversely, in the case of possible oxidative damage, the concentration of ROS drops sharply (Halliwell 2024)