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Slices were placed in a 30 C bath for 8 min

(3) Patients with severe concomitant diseases in other systems

OS can be triggered by free radicals or other oxidant species produced by either exogenous processes (environmental pollutants, drugs, viruses, bacteria, ionizing radiations, heavy metals, poor diet, and smoking) [3,4,5,6,7,8,9,10,11] or endogenous processes (such as immune cell activation, inflammation, ischemia, infection, cancer, and aging) [12,13,14,15,16,17,18,19]

The type and rate depend on the patients condition, weight, and lab tests

For example, the combination therapy can include a an antibody or immunoconjugate with at least one or more additional therapeutic agents, such as the anti-cancer agents described infra

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