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(2012) Available online at: (accessed January 30, 2021)

In this context, supplementation with ALA would undoubtedly support GPx activity by maintaining sufficient intracellular GSH pools, thereby leading to the significant enhancement of GPx expression following CSD as compared to other relatively unchanged anti-oxidative enzymes

3.3 Lipid metabolism disorder and its pathological results Lipid metabolism disorders are characterized by abnormalities in the synthesis, transport, metabolism, and catabolism of lipids, primarily including triglycerides, cholesterol, phospholipids, and free fatty acids (FFAs)

It is thought that soluble RAGE acts as a decoy receptor and is protective against the accumulation of amyloid-beta.[ref][ref] One example of how soluble RAGE acts to decrease AGEs can be found in osteoarthritis