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[1] Standard Dose 100 mcg per dose The typical maintenance dose used in practice, often given before bed and/or after fasted exercise

However, this effect was reversed by the SIRT1 inhibitor NAM

Mijangos, F., Varona, F., & Villota, N

Furthermore, sesamin-treated mice maintained higher levels of endogenous antioxidants for example, superoxide dismutase (SOD) activity was increased relative to untreated MPTP mice, and striatal TH levels were better preserved, indicating reduced dopaminergic neuron damage (66)