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Longobardi V, et al

J Cell Biol

Plant Physiol 171:914931

NMT1 depletion primarily inhibits cell replication by suppressing proliferative signaling pathways, such as the c-Src and MAPK pathways

The local context of the DNA repair complex then facilitates the activating of endogenous DNA ligase, including DNA polymerase (POL), DNA ligase II, and DNA ligase IV, to fix the damaged DNA [14]