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In multiple organisms, cellular NAD+ levels drop with age, which correlates with the onset of age-related conditions, including metabolic disorders, neurodegeneration, and cardiovascular problems

A recent study indicated that indole-3-lactic acid, which originates from Lactobacillus murinus , decreases oxidative stress and enhances intestinal stem cell growth and specialization through the control of Nrf2 [25]

Asada K, Urano M, Takahashi M

Agarwal, A., Kansal, V., Farooqi, H., Prasad, R

The inhibition of GR-1 with monoclonal antibodies has been shown to decrease tumor size and microvessel density in HCC-bearing mice (51)

Three Chinese herbal medicines promote neuroproliferation in vitro, and reverse the effects of chronic mild stress on behavior, the HPA axis, and proliferation of hippocampal precursor cell in vivo