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Selegiline, as an FDA-approved drug with a favourable drug safety profile, might be a promising candidate for repositioning to treat AGIHL or other forms of SNHLs

GSH exhibited notable interaction with YliB at the binding cleft

To identify false positives, a second aliquot of the sample was treated with DTT as described above

Ferroptosis: opportunities and challenges in treating endometrial cancer

J Biol Chem 278(50):4992049928 Wild AC, Mulcahy RT (2000) Regulation of -glutamylcysteinesynthetase subunit gene expression: insights into transcriptional control of antioxidant defenses

Kay LE, Torchia DA, Bax A (1989) Backbone dynamics of proteins as studied by nitrogen-15 inverse detected heteronuclear NMR spectroscopy: application to staphylococcal nuclease