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Epub 2017 Apr 11

This heightened activity and restlessness can be caused by the medication stimulating the central nervous system, leading to increased energy levels

Cells were permeabilized using digitonin (1 g per 10 6 platelets or 6 g per 10 6 PBMCs), and simultaneously, the N-pathway substrates (or CI substrates) malate and pyruvate were added at saturating concentrations (5 mM each)