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Otherwise, absorption of vitamin b12 interfered

The dosing regimen varies depending on whether neurological symptoms are present: With neurological involvement: 1 mg intramuscularly on alternate days until no further improvement, then 1 mg every 2 months [3] [4] Without neurological involvement: 1 mg intramuscularly three times a week for 2 weeks, then 1 mg every 2-3 months for maintenance [3] [4] There is some evidence that high-dose oral B12 (1000-2000 micrograms daily) may be effective even in some malabsorption conditions, though UK practice still generally favours intramuscular treatment in these cases

You can manage these side effects by following these tips: Eat smaller, lighter meals throughout the day, and avoid spicy, greasy, or heavy foods, as they can worsen nausea and stomach discomfort while your body adjusts to tirzepatide

The mechanism appears to involve changes in how skin bacteria produce porphyrins, compounds that can promote inflammation within hair follicles

Oral administration at 100150mg to match subcutaneous bioavailability doubles the per-dose cost, which influences protocol design when budget constraints exist

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