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The dual role of zinc on aggregation and fibrillation of -synuclein has been summarised in Figure 3

doi: 10.1016/j.bbalip.2016.02.010 299 MeersonATraurigMTOssowskiVMFlemingJMullinsMBaierLJ

In addition to the previously mentioned immune senescence- and inflammation-related mechanisms, sarcopenia is also associated with oxidative stress in skeletal muscle

GRP78, Glucose-Regulated Protein 78

As discussed before, Thioflavin-T positive glycated proteins in the bloodstream of diabetic or prediabetic patients can elicit amyloid like complicacies