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Description

(3) an alternative condensation of -glutamyl phosphate synthesized by -glutamyl kinase (Pro1 or ProB) with cysteine to form -glutamylcysteine which was further conjugated to glycine by glutathione synthetase

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Nevertheless, FSP1 has been less studied in the heart, where its relationship with ferroptosis and its precise function are poorly understood

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Metabolite quantification was acquired using Barstool [52] (see Supplementary Fig

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Abstract Background Glutathione (GSH), a pivotal non-protein thiol, can be biosynthesized through three pathways in different organisms: (1) two consecutive enzymatic reactions catalyzed by -glutamylcysteine synthetase (Gsh1 or GshA) and glutathione synthetase (Gsh2 or GshB)

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