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Down-regulation of GPX4 has been shown to sensitise to GPX4 inhibitors in prior studies 11

doi: 10.1038/s41598-019-43714-5 31 YoshimuraSNakamuraHHoraiYNakajimaHShiraishiHHayashiTet al

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Note the date opened, monitor working stability per your protocol, and dispose of the research material in line with your laboratory's chemical-waste procedures