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Sci Rep 7:43609

10.1016/j.mad.2018.03.013 21 Barr-SinoussiF.MontagutelliX

Kroemer G, Reed JC

This caution is not conservatism for its own sake: a systematic review and meta-analysis of laser therapy for melasma found that benefits are frequently offset by high recurrence and a real risk of rebound pigmentation, particularly in Fitzpatrick types IV to VI