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Additionally, the enteric nervous system (ENS), often referred to as the second brain, can also influence brain function via local signaling mechanisms

Of these four, ORF7a protein is the most potent NF-B inducer and pro-inflammatory cytokine producer.4 N-acetylcysteine is an antioxidant against reactive oxygen species and is a potent NF-B inhibitor.5 Oral N-acetylcysteine administered at 600 mg thrice daily has been shown to reduce mortality in hospitalised SARS-CoV-2 patients.6 The clinical course of our patient suggests that high-dose N-acetylcysteine antioxidant therapy was able to control the cytokine storm of SARS-CoV-2 infection

10.5897/AJPS2019.1911 127

Future research should map K-Hcy-modified secretomes and other intracellular proteins in corpus cavernosum to provide a more comprehensive understanding of how K-Hcy contributes to ED

10.1042/BCJ20190072 Biochem

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