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Chronic inhibition may theoretically disrupt: S-adenosylmethionine (SAMe) balance Homocysteine metabolism Epigenetic regulation Long-term alteration of methylation pathways may carry systemic consequences that are not yet understood, including potential impacts on cardiovascular and neurological health

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Typo correction: "...therefore lacks understanding of the severity of B12 nerve DESTRUCTION." Thanks for posting this link it made interesting reading

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