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Please check with your doctor or pharmacist if you are not completely sure

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Brealey D, Karyampudi S, Jacques TS, Novelli M, Stidwill R, Taylor V, et al

The efficacy evidence for edaravone is primarily derived from clinical trials in East Asian populations, and its benefits have been less consistently replicated in Western studies and real-world settings outside of Japan

However, it is important to recognize that ongoing use is typically required to maintain these benefits

Overuse of medications such as metformin, proton pump inhibitors, histamine H2 blockers, and oral contraceptive pills can reduce B12 levels