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Microbiota-derived metabolites are key mediators of host-microbe interactions ( 2.3 Bidirectional neuroendocrine crosstalk In addition to regulating host metabolism and immune responses, the gut microbiota is recognized to play a critical role in the production of neurotransmitters and engages in complex bidirectional communication with the hypothalamicpituitarygonadal (HPG) axis, contributing significantly to the pathogenesis and potential treatment of PCOS

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Study has shown that Nrf2 is highly expressed in cancer tissues of NSCLC patients and can regulate the sensitivity of NSCLC cells to ferroptosis induced by Cys 2 deprivation [88]

Materials and Methods Cell Culture U-87 MG cells were maintained in Eagles Minimum Essential Medium supplemented with 10% FBS and 1x pen-strep

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