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Accordingly, PPARA and its target gene, CPT1A , were significantly downregulated in both primary hepatocytes (Extended Data Fig

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was financed by grants from the Swedish state under the agreement between the Swedish government and the county councils, the ALF-agreement (grant numbers ALFGBG-1005471, ALFGBG-965923, ALFGBG-81392, ALFGBG-771071), the Alzheimerfonden (grant numbers AF-842471, AF-737641, AF-929959, AF-939825), the Swedish Research Council (grant numbers 2019-02075, 2019-02075_15), Stiftelsen Psykiatriska Forskningsfonden and The Swedish Brain Foundation FO2024-0097

doi: 10.1210/jc.2006-1527 49 CottrellEMaharajAWilliamsJChatterjeeSCirilloGMiraglia Del GiudiceEet al

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