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People recovering from ACL surgery, tendon injuries, or joint problems also see major improvements

144 A more recent meta-analysis by Yang et al examined metformin use and neuropathy and found no association, highlighting similar issues in terms of the lack of randomised controlled trials, small sample size and varying study design as described above

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The recurrence rate was 7 (3.0%) in the RPH + sMMH group, and the recurrence rate was 15 (7.8%) in the MMH group, there was a significant difference in recurrence rate after 12 months post operation (P = 0.032)