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The expression levels of pro-inflammatory cytokines were also significantly reduced, and the results overall suggest that Grx1-regulated S-glutathionylation in macrophages plays a protective role in acute lung injury (Figure 2)

265,266 When GLP-1 binds to its receptors in the hypothalamus, it activates specific neurons, including those that promote satiety (POMC/CART neurons) and inhibits those that induce hunger (NPY/AgRP neurons), thereby enhancing the feeling of fullness and reducing food intake