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Flow-through particles have a bimodal pore configuration, in which both small diffusion pores and large flow-through pores are present

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doi: 10.1016/j.intimp.2024.113187 Summary Keywords gouty arthritis, disease staging, proteomics, validation, joint cavity effusion, tophi, ferroptosis Citation Xiao N, Lu H, Zeng S, Yan H, Yang Q, Sheng L, Chen B, Xu Y, Zhang J, Xie J, Zhou W, Li Z and Xie Z (2026) Exploring the inflammatory origins of gouty arthritis: mechanistic studies based on local lesion proteomics and validation

That means for every milligram you inject, roughly 0.8mg reaches systemic circulation in active form

doi: 10.3390/PLANTS12040953/S1 195 NkoboleN.PrinslooG