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Your doctor can discuss all the options, their benefits, and risks, and help you find the most suitable therapy for you

Reithmeier showed in 1987 that the structure of another calcium-binding protein, calsequestrin (which binds 40-50 calcium ions and is characterized by high levels of acidic residues), is calcium-sensitive as well, as this protein was rapidly degraded by trypsin in the absence of calcium, but showed remarkable stability in calcium-loaded form (Ohnishi and Reithmeier, 1987)