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The redundancy of parallel growth factor signals can bypass KRAS blockade, underlying intrinsic resistance to KRAS G12C inhibitors (96)

Heavy drinkers metabolize alcohol faster through MEOS induction and CYP2E1 upregulation, but this increased clearance speed does not reduce impairment or protect the liver

Modeling and sequence analysis indicated that both molecules may share a lineal epitope in their N-terminal domain ( Cockroach allergy has important clinical implications due to its association with emergency room admissions (35, 36)

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When oxidative stress overwhelms cellular defenses, it can impair the 26S proteasome, leading to the accumulation of ubiquitinated proteins and disrupting protein homeostasis