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Hydrochlorothiazide should be used cautiously in patients with renal disease such as severe renal impairment or renal failure

Just so you know, the formaldehyde released at typical use concentrations (up to 0.6% in the EU and typically 0.1-0.3% in the US) are tiny

Mood, sleep, and workout recovery improvements compound over the first 2 to 3 weeks