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As also shown in related structural studies, the general base Glu 256 could further support the hydride transfer step of MSA-DH catalysis (Kim et al., 2009

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ELAVL1 was overexpressed in many tumors, including kidney chromophore, rectum and colon adenocarcinomas, lung and cervical squamous cell carcinomas, and breast cancer carcinoma, confirming previous data from the literature 29,79

Drug stock solutions were prepared with dimethyl sulfoxide (DMSO) and diluted to obtain a nontoxic working concentration wherein DMSO did not exceed 0.1%

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