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These modifications can lead to mutations, genomic instability, and if not adequately repaired, contribute to carcinogenesis and other genetic disorders [39]

21252128, 1995 [14] J

- GSSG GSH - GSSG (precursors) GSH 3

2.2.5 Gut microbiota-based therapeutic interventions 2.2.5.1 Probiotics The results of human clinical trials (see Table 5) suggest that probiotics may be beneficial as a supportive therapy for PD

In summary, while small observational uses of alpha-lipoic acid in pregnancy have not reported acute problems, the absence of comprehensive safety data means ALA is not routinely recommended for pregnant or lactating women

Ni B, Liu Y, Gao X, Cai M, Fu J, Yin X et al (2022) Isoliquiritigenin attenuates emodin-induced hepatotoxicity in vivo and in vitro through Nrf2 pathway