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Ethics declarations Ethics approval and consent to participate This research has been conducted using the UK Biobank Resource under application number 42468 and other large studies and consortia providing publicly available summary statistics

Pentoxifylline (PTX) Although most of the oral medications investigated for the treatment of PD have shown poor or indeterminate outcomes in controlled studies, PTX has fared much better

The L-carnitine is a molecule naturally present in our bodies, derived from the combination of two amino acids: lysine and methionine

L-arginine: L-arginine is an amino acid that plays a crucial role in immune function and blood vessel health

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