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Because PD effects are measurable at achievable oral exposures, SFN-type compounds are suitable candidates for initial human proof-of-mechanism work (Yan and Yan, 2023

Overdijk MB, Jansen JHM, Nederend M, Lammerts van Bueren JJ, Groen RWJ, Parren PWHI

It stimulates collagen and elastin synthesis through cellular signaling rather than requiring increased protein substrate availability

doi:10.1002/14651858.CD013325.pub2 Chen PY, Lee WC, Chuang YC

doi: 10.1186/s43556-025-00275-6 79 ShaoHKaplanHJSunD

It is vital for both conceiving and pregnant women to consume a nutritious diet that is not lacking in micronutrients and essential amino acids