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Purified RNA was measured by Nanodrop (Thermo Fisher) and reverse transcription was performed using Revert Aid First Strand cDNA Synthesis Kit (Thermo Scientific)

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thermodenitrificans where a homotetrameric precursor is initially produced, which underwent autocatalysis after incubation at 45C for 48 h ( Analysis of the recently solved crystal structure of the T399A precursor mimic of BlGGT gave interesting insights

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