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Afterwards, the kinetic models are explained and metabolic turnover rates are calculated

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Furthermore, the SIRT1 knockdown experiment demonstrates that the protective effect of IA against ferroptosis is partially abrogated, thereby reinforcing the notion that IA enhances mitochondrial function, inhibits myocardial lipid peroxidation, and alleviates ferroptosis via activation of the SIRT1 pathway [202]

doi: 10.1016/j.ibror.2017.03.001 295 WangG

regulation of peroxisome proliferator-activated receptor-gamma activity by mammalian target of rapamycin and amino acids in adipogenesis

Concepts such as virtual digital twins for nutrition envision a computational replica of an individual that integrates genetic, metabolomic, immune, microbiome and behavioral data to simulate the impact of dietary interventions in silico (254)