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The LNs from mice injected s.c

Dendritic cells (DCs) act as central hubsIRE combined with VMT/CaO 2 NSs captures tumor antigens to form in situ vaccines that promote DC migration (105)

As shown in Supplemental Figure 5, B and C, we observed lower Na/K/Cl cotransport and Na/H exchange activities in RBCs from mitapivat-treated 4.2 / mice when compared with vehicle-treated animals, suggesting an improved RBC ion homeostasis related to the amelioration of RBC membrane mechanical stability

The biomarkers, some of which can act as risk factors were grouped into 8 models of DCM (AGEs, cardiometabolic, glycaemic, lipid, oxidative stress, inflammatory, the molecules of signalling pathways and fibrosis) in which a total of 37 biomarkers were evaluated