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Oncogenic Myc induces expression of glutamine synthetase through promoter demethylation

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Endogenous glutamine is rate-limiting for anti-Cd3 and anti-Cd28 induced Cd4+ T-cell proliferation and glycolytic activity under hypoxia and normoxia

AEs were not addressed (Hillelsohn 2012), reported as not occurring (Payne 2009), or reported as one case of minor bladder perforation treated with an indwelling catheter for one week (Jhang 2013)