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Shreya et al., 2022)

Moreover, this pathway can be activated by Ring finger protein 1 (Ring1), which is highly expressed in HCC, and in this way contributes to promoting the transformation of Hepatic progenitor cells (HPC) into CSC (119)

135 Numerous medications and other substances have been used in this therapy, including the anesthetic lidocaine, corticosteroid drugs, botulinum toxin A, platelet-rich plasma, sodium bicarbonate, and even sterile saline