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For example, certain miRNAs (e.g., miR-124) have been loaded into MSCs to suppress tumor growth by inhibiting oncogenic pathways

However, large-scale clinical trials specifically evaluating IV therapy combined with HA injections for knee OA are lacking

The expression of the CB1-R has been found in the glutamatergic corticostriatal afferences in both dorsal and ventral striatum [23, 24] and the projections of striatal GABAergic neurons innervating the globus pallidus (GPi and GPe) and the substantia nigra pars reticulata (SNpr) [25, 26]

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Different forms of cell death may exhibit functional crosstalk, with ferroptosis, necroptosis, pyroptosis, and oxeiptosis all requiring the generation of ROS (Fig