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However, for ARPE-19 cells, ATCC recommends a mixture of Dulbeccos Modified Eagle Medium and Hams F12 Medium with 17.5 mM glucose

24 The marked discrepancy between our calculated genetic prevalence data for WD (if extrapolated, suggesting approximately 9,000 current cases of WD in the UK) and the considerably lower number of clinically diagnosed WD patients is likely to be at least partially due to reduced penetrance of ATP7B mutations