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Life Sci 71: 30313045

The TEV protease and the -mercaptoethanol were added in the pooled fraction with target protein to TEV protease ratio of 1:10 (w/w) and the final concentration of 10 mM, respectively, to cleave 6HFh8 and dialyzed against 1 PBS with 150 mM NaCl at 4 C overnight

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EVs with TfR deficiency lost their iron-chelating capacity and cardioprotective effect in post-MI hearts

The model fit was impaired without lag time and not relevantly improved by a two-compartment model

indicated that over half of the participants experienced full lesion healing and symptom abatement, with another 30% witnessing substantial lesion diminution and symptom relief