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In vitro glutathione peroxidase mimicry of ebselen is linked to its oxidation of critical thiols on key cerebral suphydryl proteins - A novel component of its GPx-mimic antioxidant mechanism emerging from its thiol-modulated toxicology and pharmacology

Preclinical studies and clinical trials demonstrate that targeting metabolic pathways can improve cardiac remodeling, functional capacity, and long-term outcomes

Martin MA, et al

Proc Natl Acad Sci USA (2005) 102(39):1390914

Efficient compound delivery : This technology engineers the phospholipids to encapsulate the compound, in order to bypass the digestive processes that normally degrade or limit compound absorption and to bring the power of intravenous therapy into convenient oral delivery

In individuals with insulin resistance, the pancreas overproduces insulin to manage glucose levels