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Hu, J., Shen, J

The choice of terms was based on standardized and widely accepted definitions in relevant fields

Inhibitors of the NLRP3 inflammasome not only block pyroptosis (see above) but also limit the release of pro-inflammatory cytokines, conferring robust protection in preclinical ischemia/reperfusion models [59, 210, 211]

However, the variability in age of onset depends not only on the repeat number (50%), but also on modifier genes, the number of stabilizing interruptions, somatic mosaicism, and the instability of the expansion during life