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However, large-scale human clinical trials remain limited

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Fifty units of (Speywood) botulinum toxin type A (Dysport) were subcutaneously injected in eight points distributed mostly along V2 in the lateral periorbital area and in three injection points in the inferolateral area taking care not to infiltrate too much directly under the eye to minimise potential aesthetic side effects

In vitro, GADD45 overexpression in HepG2 cells significantly suppressed fatty acid-induced expression of these genes, whereas GADD45 knockdown enhanced their expression and lipid accumulation

Dextran iron is formed by the complexation of dextran (molecular weight 5000-7500) with iron ions, creating a stable colloidal solution

Where neurological involvement is suspected, IM hydroxocobalamin must be started urgently without waiting for blood test results to prevent irreversible nerve damage